Tbcel | tubulin folding cofactor E-like

GeneMGI:1925543Synonyms: E130107N23Rik, Lrrc35

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Nervous system Vision/eye Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal optic disk morphology1 supporting datasetTbcelem1(IMPC)JhomozygoteEarly adult7.47x10-5 
decreased grip strength1 supporting datasetTbcelem1(IMPC)JhomozygoteEarly adult2.03x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tbcelem1(IMPC)JExon Deletionmouse
Tbceltm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Tbceltm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Tbceltm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Tbceltm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Tbceltm3a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Tbceltm3e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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