Atrip | ATR interacting protein

GeneMGI:1925349Synonyms: 6620401K05Rik

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

17 No significant impact

5 Not tested

Gene metrics:5Significant phenotypes
1Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

decreased fasting circulating glucose level1 supporting datasetAtriptm1b(KOMP)WtsiheterozygoteEarly adult2.18x10-10 
increased circulating sodium level1 supporting datasetAtriptm1b(KOMP)WtsiheterozygoteEarly adult3.25x10-8 
embryonic lethality prior to organogenesis1 supporting datasetAtriptm1b(KOMP)WtsihomozygoteE9.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetAtriptm1b(KOMP)WtsihomozygoteEarly adultN/A * 
increased circulating chloride level1 supporting datasetAtriptm1b(KOMP)WtsiheterozygoteEarly adult5.37x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Atriptm119157(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Atriptm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Atriptm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Atriptm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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