Mccc2 | methylcrotonoyl-Coenzyme A carboxylase 2 (beta)

GeneMGI:1925288Synonyms: 4930552N12Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Nervous system Hematopoietic system Skeleton Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased prepulse inhibition	1 supporting dataset	Mccc2^em1(IMPC)J	heterozygote	Early adult	5.13x10^-5
increased erythrocyte cell number	1 supporting dataset	Mccc2^em1(IMPC)J	heterozygote	Early adult	4.83x10^-7
decreased bone mineral density	1 supporting dataset	Mccc2^em1(IMPC)J	heterozygote	Early adult	5.91x10^-5
decreased mean corpuscular volume	1 supporting dataset	Mccc2^em1(IMPC)J	heterozygote	Early adult	1.87x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Mccc2^em1(IMPC)J	homozygote	Early adult	N/A ^*
decreased mean corpuscular hemoglobin	1 supporting dataset	Mccc2^em1(IMPC)J	heterozygote	Early adult	9.32x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mccc2.

Associated images

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Histopathology

There is no histopathology data found for Mccc2.

IMPC related publications

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External links

No external links available for Mccc2.

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*Mccc2^em1(IMPC)J*	Exon Deletion	‌	mouse
*Mccc2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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