Fbxo42 | F-box protein 42

GeneMGI:1924992Synonyms: 6720460I06Rik

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Skeleton Mortality/aging Cardiovascular system

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased circulating calcium level	1 supporting dataset	Fbxo42^em1(IMPC)J	heterozygote	Early adult	3.75x10^-10
thrombocytosis	1 supporting dataset	Fbxo42^em1(IMPC)J	heterozygote	Early adult	1.53x10^-7
preweaning lethality, complete penetrance	1 supporting dataset	Fbxo42^em1(IMPC)J	homozygote	Early adult	N/A ^*
decreased circulating aspartate transaminase level	1 supporting dataset	Fbxo42^em1(IMPC)J	heterozygote	Early adult	4.2x10^-9
increased bone mineral content	1 supporting dataset	Fbxo42^em1(IMPC)J	heterozygote	Early adult	5.58x10^-5
decreased circulating bilirubin level	1 supporting dataset	Fbxo42^em1(IMPC)J	heterozygote	Early adult	3.73x10^-11
prolonged QRS complex duration	1 supporting dataset	Fbxo42^em1(IMPC)J	heterozygote	Early adult	3.04x10^-5
decreased circulating alanine transaminase level	1 supporting dataset	Fbxo42^em1(IMPC)J	heterozygote	Early adult	8.26x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fbxo42.

Associated images

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Histopathology

There is no histopathology data found for Fbxo42.

IMPC related publications

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External links

No external links available for Fbxo42.

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*Fbxo42^em1(IMPC)J*	Exon Deletion	‌	mouse
*Fbxo42^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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