Mthfd1l | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

GeneMGI:1924836Synonyms: Fthfsdc1, 2410004L15Rik

Physiological systems

20 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Mortality/aging

19 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes



preweaning lethality, complete penetrance	1 supporting dataset		Mthfd1l^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult		N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mthfd1l.

Associated images

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Histopathology

There is no histopathology data found for Mthfd1l.

IMPC related publications

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External links

No external links available for Mthfd1l.

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*Mthfd1l^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Mthfd1l^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Mthfd1l^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Mthfd1l^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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