Mboat7 | membrane bound O-acyltransferase domain containing 7

GeneMGI:1924832Synonyms: Lpiat1, mBB1, +2 more

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Mortality/aging

14 No significant impact

4 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues

Phenotypes

increased lymphocyte cell number1 supporting datasetMboat7tm1b(KOMP)WtsiheterozygoteEarly adult9.53x10-6 
preweaning lethality, incomplete penetrance1 supporting datasetMboat7tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
decreased lean body mass1 supporting datasetMboat7tm1b(KOMP)WtsiheterozygoteEarly adult1.4x10-5 
small seminal vesicle1 supporting datasetMboat7tm1b(KOMP)WtsiheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mboat7tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Mboat7tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Mboat7tm1c(KOMP)WtsiWild type floxed exon (post-Flp)mouse
Mboat7tm1e(KOMP)WtsiTargeted, non-conditional allelees cell

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