Spns3 | SPNS lysolipid transporter 3, sphingosine-1-phosphate (putative)

GeneMGI:1924827Synonyms: 9830002I17Rik

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Reproductive system Immune system Growth/size/body region Hematopoietic system Skeleton Renal/urinary system

12 No significant impact

6 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal sternum morphology1 supporting datasetSpns3em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal uterus morphology1 supporting datasetSpns3em1(IMPC)TcphomozygoteEarly adultN/A * 
enlarged urinary bladder1 supporting datasetSpns3em1(IMPC)TcphomozygoteEarly adultN/A * 
increased eosinophil cell number1 supporting datasetSpns3em1(IMPC)TcphomozygoteEarly adult1.97x10-6 
increased red blood cell distribution width1 supporting datasetSpns3em1(IMPC)TcphomozygoteEarly adult1.78x10-5 
enlarged kidney1 supporting datasetSpns3em1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Spns3em1(IMPC)TcpExon Deletionmouse
Spns3tm446(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Spns3tm446(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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