Kcnt1 | potassium channel, subfamily T, member 1
Physiological systems
20 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Immune system Vision/eye Hematopoietic system Behavior/neurological Renal/urinary system
15 No significant impact
4 Not tested
Data collections
Gene metrics:10Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| small spleen | 1 supporting dataset | Kcnt1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| small kidney | 1 supporting dataset | Kcnt1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| decreased anxiety-related response | 1 supporting dataset | Kcnt1em1(IMPC)Mbp | homozygote | Early adult | 9.55x10-6 | ||
| decreased thigmotaxis | 2 supporting datasets | Kcnt1em1(IMPC)Mbp | homozygote | Early adult | 7.03x10-7 | ||
| abnormal spleen morphology | 1 supporting dataset | Kcnt1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal eye morphology | 1 supporting dataset | Kcnt1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| decreased locomotor activity | 1 supporting dataset | Kcnt1em1(IMPC)Mbp | homozygote | Early adult | 1.84x10-10 | ||
| abnormal kidney morphology | 1 supporting dataset | Kcnt1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal behavior | 1 supporting dataset | Kcnt1em1(IMPC)Mbp | homozygote | Early adult | 7.53x10-7 | ||
| anophthalmia | 1 supporting dataset | Kcnt1em1(IMPC)Mbp | homozygote | Early adult | N/A * |
| | | | | | | | | | |
External links
No external links available for Kcnt1.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Kcnt1em1(IMPC)Mbp | Exon Deletion | | mouse |
| Kcnt1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Kcnt1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |