Pacs2 | phosphofurin acidic cluster sorting protein 2

GeneMGI:1924399Synonyms: 6720425G15Rik, Pacs1l

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Limbs/digits/tail Nervous system Hematopoietic system Behavior/neurological Skeleton

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased hemoglobin content	1 supporting dataset	Pacs2^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	1.46x10^-5
increased startle reflex	5 supporting datasets	Pacs2^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2.96x10^-28
decreased prepulse inhibition	2 supporting datasets	Pacs2^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2.02x10^-5
short tibia	1 supporting dataset	Pacs2^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	1.76x10^-5
abnormal behavior	3 supporting datasets	Pacs2^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2.63x10^-7
increased total body fat amount	1 supporting dataset	Pacs2^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2.72x10^-5
increased circulating alkaline phosphatase level	1 supporting dataset	Pacs2^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	3.21x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pacs2.

Associated images

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Histopathology

There is no histopathology data found for Pacs2.

IMPC related publications

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External links

No external links available for Pacs2.

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*Pacs2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Pacs2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Pacs2^{tm80423(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes