Mtmr2 | myotubularin related protein 2

GeneMGI:1924366Synonyms: 6030445P13Rik

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system Behavior/neurological

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased startle reflex1 supporting datasetMtmr2em1(IMPC)HmguhomozygoteEarly adult4.6x10-6 
increased mean platelet volume1 supporting datasetMtmr2em1(IMPC)HmguhomozygoteEarly adult3.91x10-6 
increased blood urea nitrogen level1 supporting datasetMtmr2em1(IMPC)HmguhomozygoteEarly adult7.73x10-6 
increased circulating creatinine level1 supporting datasetMtmr2em1(IMPC)HmguhomozygoteEarly adult2.38x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mtmr2em1(IMPC)HmguExon Deletionmouse
Mtmr2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Mtmr2tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Mtmr2tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell

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