Os9 | amplified in osteosarcoma
Physiological systems
18 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Growth/size/body region Skeleton Craniofacial
15 No significant impact
6 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
vertebral fusion | 1 supporting dataset | Os9tm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.92x10-5 | ||
abnormal tooth morphology | 1 supporting dataset | Os9tm1a(EUCOMM)Wtsi | homozygote | Early adult | 9.12x10-5 | ||
abnormal snout morphology | 1 supporting dataset | Os9tm1a(EUCOMM)Wtsi | homozygote | Early adult | 2.73x10-6 | ||
abnormal cranium morphology | 1 supporting dataset | Os9tm1a(EUCOMM)Wtsi | homozygote | Early adult | 1.4x10-5 |
| | | | | | | | | |
Human diseases caused by Os9 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Os9.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
Os9tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
Os9tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Os9tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Os9tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
Os9tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |