Cep83 | centrosomal protein 83

GeneMGI:1924298Synonyms: 5730513H21Rik, 2600001G24Rik, +2 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Embryo Growth/size/body region Mortality/aging Cardiovascular system

14 No significant impact

5 Not tested

Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:73Adult tissues
29Embryo tissues

Phenotypes

abnormal embryo size1 supporting datasetCep83tm1.1(KOMP)VlcghomozygoteE9.5N/A * 
embryonic growth retardation1 supporting datasetCep83tm1.1(KOMP)VlcghomozygoteE9.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsCep83tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetCep83tm1.1(KOMP)VlcghomozygoteE12.5N/A * 
abnormal pericardium morphology1 supporting datasetCep83tm1.1(KOMP)VlcghomozygoteE9.5N/A * 
edema1 supporting datasetCep83tm1.1(KOMP)VlcghomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cep83tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Cep83tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Cep83tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cep83tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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