Mrap | melanocortin 2 receptor accessory protein

GeneMGI:1924287Synonyms: 1110025G12Rik, C21ORF61

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Integument Embryo Growth/size/body region Skeleton Mortality/aging

15 No significant impact

4 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsMrapem1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal sternum morphology1 supporting datasetMrapem1(IMPC)TcpheterozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetMrapem1(IMPC)TcpheterozygoteEarly adultN/A * 
abnormal embryo size1 supporting datasetMrapem1(IMPC)TcphomozygoteE15.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mrapem1(IMPC)TcpExon Deletionmouse
Mraptm364278(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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