Slc9a8 | solute carrier family 9 (sodium/hydrogen exchanger), member 8

GeneMGI:1924281Synonyms: 1200006P13Rik, NHE8, +1 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Pigmentation Vision/eye

18 No significant impact

4 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

abnormal retina morphology2 supporting datasetsSlc9a8tm1a(KOMP)WtsihomozygoteEarly adult2.06x10-9 
abnormal eye morphology1 supporting datasetSlc9a8tm1a(KOMP)WtsihomozygoteEarly adult7.65x10-7 
abnormal retina pigmentation2 supporting datasetsSlc9a8tm1a(KOMP)WtsihomozygoteEarly adult2.06x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

adrenal glandheterozygoten/a100% (1/1)0.7% (4/570)
aortaheterozygoten/an/a0.19% (1/533)
blood vesselheterozygoten/a0% (0/1)0% (0/173)
boneheterozygoten/a0% (0/2)0% (0/394)
brainheterozygoten/a100% (2/2)0.86% (5/579)
brainstemheterozygoten/an/a0.41% (2/490)
brown adipose tissueheterozygoten/a0% (0/2)0% (0/588)
cartilage tissueheterozygoten/a0% (0/2)0.22% (1/454)
cerebellumheterozygoten/an/a0.56% (3/532)
cerebral cortexheterozygoten/an/a0.41% (2/491)
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Associated images

Histopathology

IMPC related publications

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Slc9a8tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Slc9a8tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Slc9a8tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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