Scfd1 | Sec1 family domain containing 1

GeneMGI:1924233Synonyms: RA410, 3110021P21Rik, +1 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Integument Hematopoietic system Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased mean corpuscular hemoglobin1 supporting datasetScfd1em1(IMPC)TcpheterozygoteEarly adult7.82x10-5 
preweaning lethality, complete penetrance3 supporting datasetsScfd1em1(IMPC)TcphomozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetScfd1em1(IMPC)TcphomozygoteE9.5N/A * 
abnormal skin morphology1 supporting datasetScfd1em1(IMPC)TcpheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Scfd1em1(IMPC)TcpExon Deletionmouse
Scfd1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Scfd1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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