Emsy | EMSY, BRCA2-interacting transcriptional repressor

GeneMGI:1924203Synonyms: 2210018M11Rik

Physiological systems

21 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Limbs/digits/tail Hematopoietic system Skeleton Cardiovascular system Mortality/aging Renal/urinary system

10 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:15Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal testis morphology	1 supporting dataset	Emsy^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Emsy^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
small seminal vesicle	1 supporting dataset	Emsy^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Emsy^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
enlarged testis	1 supporting dataset	Emsy^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
vertebral transformation	1 supporting dataset	Emsy^{em1(IMPC)Ccpcz}	heterozygote	Early adult	9.3x10^-5
increased NK cell number	1 supporting dataset	Emsy^{em1(IMPC)Ccpcz}	heterozygote	Early adult	1.5x10^-7
impaired glucose tolerance	1 supporting dataset	Emsy^{em1(IMPC)Ccpcz}	heterozygote	Early adult	9.72x10^-6
enlarged epididymis	1 supporting dataset	Emsy^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal kidney morphology	2 supporting datasets	Emsy^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Emsy.

Associated images

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Histopathology

There is no histopathology data found for Emsy.

IMPC related publications

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External links

No external links available for Emsy.

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*Emsy^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Emsy^{tm173015(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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