Arrdc5 | arrestin domain containing 5

GeneMGI:1924170Synonyms: 1700013E09Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Vision/eye Hematopoietic system

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

male infertility1 supporting datasetArrdc5tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
abnormal retina morphology1 supporting datasetArrdc5tm1b(EUCOMM)WtsihomozygoteEarly adult5.28x10-5 
increased mean corpuscular hemoglobin1 supporting datasetArrdc5tm1b(EUCOMM)WtsihomozygoteEarly adult7.31x10-5 
increased circulating fructosamine level1 supporting datasetArrdc5tm1b(EUCOMM)WtsihomozygoteEarly adult3.62x10-5 
increased circulating alkaline phosphatase level1 supporting datasetArrdc5tm1b(EUCOMM)WtsihomozygoteEarly adult8.61x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Arrdc5tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Arrdc5tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Arrdc5tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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