Memo1 | mediator of cell motility 1

GeneMGI:1924140Synonyms: 0610016J10Rik, D930048L02Rik

Physiological systems

22 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Embryo Growth/size/body region Behavior/neurological Mortality/aging Cardiovascular system

16 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:50Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:

Life Stage:



abnormal embryo size	1 supporting dataset	Memo1^{tm1b(EUCOMM)Wtsi}	homozygote	E18.5	N/A ^*
hemorrhage	1 supporting dataset	Memo1^{tm1b(EUCOMM)Wtsi}	homozygote	E18.5	N/A ^*
thick ventricular wall	2 supporting datasets	Memo1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	6.02x10^-5
edema	1 supporting dataset	Memo1^{tm1b(EUCOMM)Wtsi}	homozygote	E18.5	N/A ^*
abnormal pericardium morphology	1 supporting dataset	Memo1^{tm1b(EUCOMM)Wtsi}	homozygote	E12.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Memo1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
unresponsive to tactile stimuli	1 supporting dataset	Memo1^{tm1b(EUCOMM)Wtsi}	heterozygote	E18.5	N/A ^*
trunk curl	1 supporting dataset	Memo1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	3.79x10^-7
unresponsive to tactile stimuli	1 supporting dataset	Memo1^{tm1b(EUCOMM)Wtsi}	homozygote	E18.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Memo1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Memo1.

Associated images

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Histopathology

There is no histopathology data found for Memo1.

IMPC related publications

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External links

No external links available for Memo1.

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*Memo1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Memo1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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