Dtl | denticleless E3 ubiquitin protein ligase

GeneMGI:1924093Synonyms: 5730564G15Rik, 2810047L02Rik

Physiological systems

13 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Behavior/neurological

12 No significant impact

11 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:1Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased grip strength1 supporting datasetDtltm1b(EUCOMM)WtsiheterozygoteEarly adult8.06x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dtltm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Dtltm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Dtltm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Dtltm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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