Usp42 | ubiquitin specific peptidase 42
Physiological systems
20 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Reproductive system Adipose tissue Growth/size/body region Vision/eye Behavior/neurological
15 No significant impact
4 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
| abnormal behavior | 4 supporting datasets | Usp42tm2a(EUCOMM)Wtsi | homozygote | Early adult | 4.84x10-17 | ||
| decreased lean body mass | 1 supporting dataset | Usp42tm2a(EUCOMM)Wtsi | homozygote | Early adult | 1.58x10-6 | ||
| decreased body weight | 2 supporting datasets | Usp42tm2a(EUCOMM)Wtsi | homozygote | Early adult | 5.49x10-6 | ||
| abnormal lens morphology | 1 supporting dataset | Usp42tm2a(EUCOMM)Wtsi | homozygote | Early adult | 3.8x10-5 | ||
| increased total body fat amount | 1 supporting dataset | Usp42tm2a(EUCOMM)Wtsi | homozygote | Early adult | 5.48x10-6 | ||
| hyperactivity | 1 supporting dataset | Usp42tm2a(EUCOMM)Wtsi | homozygote | Early adult | 7.72x10-5 | ||
| decreased body length | 1 supporting dataset | Usp42tm2a(EUCOMM)Wtsi | homozygote | Early adult | 1.94x10-5 | ||
| male infertility | 1 supporting dataset | Usp42tm2a(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| cataract | 1 supporting dataset | Usp42tm2a(EUCOMM)Wtsi | homozygote | Early adult | 2.23x10-5 |
| | | | | | | | | | |
| adrenal gland | heterozygote | n/a | 0% (0/2) | 0.7% (4/570) |
| aorta | heterozygote | n/a | n/a | 0.19% (1/533) |
| blood vessel | heterozygote | n/a | 0% (0/2) | 0% (0/173) |
| bone | heterozygote | n/a | 0% (0/2) | 0% (0/394) |
| brain | heterozygote | n/a | 100% (2/2) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | n/a | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | 0% (0/2) | 0.22% (1/454) |
| cerebellum | heterozygote | n/a | n/a | 0.56% (3/532) |
| cerebral cortex | heterozygote | n/a | n/a | 0.41% (2/491) |
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Usp42.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Usp42tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Usp42tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Usp42tm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Usp42tm3a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |