Usp42 | ubiquitin specific peptidase 42

GeneMGI:1924050Synonyms: 2410140K03Rik, 3110031A07Rik, +2 more

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Reproductive system Adipose tissue Growth/size/body region Vision/eye Behavior/neurological

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal behavior	4 supporting datasets	Usp42^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	4.84x10^-17
decreased lean body mass	1 supporting dataset	Usp42^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	1.58x10^-6
decreased body weight	2 supporting datasets	Usp42^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	5.49x10^-6
abnormal lens morphology	1 supporting dataset	Usp42^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	3.8x10^-5
increased total body fat amount	1 supporting dataset	Usp42^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	5.48x10^-6
hyperactivity	1 supporting dataset	Usp42^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	7.72x10^-5
decreased body length	1 supporting dataset	Usp42^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	1.94x10^-5
male infertility	1 supporting dataset	Usp42^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
cataract	1 supporting dataset	Usp42^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	2.23x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Usp42.

Associated images

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Histopathology

There is no histopathology data found for Usp42.

IMPC related publications

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External links

No external links available for Usp42.

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*Usp42^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Usp42^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Usp42^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Usp42^{tm3a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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