Mfsd2a | MFSD2 lysolipid transporter A, lysophospholipid

GeneMGI:1923824Synonyms: major facilitator superfamily domain containing 2A, 1700018O18Rik, +1 more

Physiological systems

22 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Reproductive system Endocrine/exocrine gland Embryo Growth/size/body region Mortality/aging

17 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

2Associated diseases

Expression examined in:73Adult tissues

29Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, incomplete penetrance	3 supporting datasets	Mfsd2a^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Mfsd2a^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*
enlarged testis	1 supporting dataset	Mfsd2a^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*
abnormal embryo size	1 supporting dataset	Mfsd2a^{tm1b(KOMP)Wtsi}	homozygote	E15.5	N/A ^*
enlarged epididymis	1 supporting dataset	Mfsd2a^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*
abnormal epididymis morphology	1 supporting dataset	Mfsd2a^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mfsd2a.

Associated images

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Histopathology

There is no histopathology data found for Mfsd2a.

IMPC related publications

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External links

No external links available for Mfsd2a.

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*Mfsd2a^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Mfsd2a^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Mfsd2a^{tm36696(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Mfsd2a^{tm36696(L1L2_st0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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