Prss8 | serine protease 8 (prostasin)
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Hematopoietic system Behavior/neurological Mortality/aging
14 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues
| increased fasting circulating glucose level | 1 supporting dataset | Prss8tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 5.23x10-5 | ||
| decreased mean corpuscular hemoglobin concentration | 1 supporting dataset | Prss8tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 2.79x10-7 | ||
| decreased thigmotaxis | 2 supporting datasets | Prss8tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 5.81x10-5 | ||
| increased grip strength | 1 supporting dataset | Prss8tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 8.32x10-5 | ||
| cataract | 1 supporting dataset | Prss8tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 6.7x10-6 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Prss8tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * |
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External links
No external links available for Prss8.
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| Prss8tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Prss8tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Prss8tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |