Atg2b | autophagy related 2B

GeneMGI:1923809Synonyms: 2410024A21Rik, C630028L02Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Hearing/vestibular/ear Vision/eye Behavior/neurological Cardiovascular system

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased thigmotaxis2 supporting datasetsAtg2bem1(IMPC)JhomozygoteEarly adult8.95x10-7 
decreased exploration in new environment1 supporting datasetAtg2bem1(IMPC)JhomozygoteEarly adult2.93x10-8 
abnormal auditory brainstem response1 supporting datasetAtg2bem1(IMPC)JhomozygoteEarly adult9.53x10-6 
increased heart weight1 supporting datasetAtg2bem1(IMPC)JhomozygoteEarly adult1.56x10-7 
increased circulating cholesterol level1 supporting datasetAtg2bem1(IMPC)JhomozygoteEarly adult4.11x10-7 
abnormal retina morphology1 supporting datasetAtg2bem1(IMPC)JhomozygoteEarly adult1.62x10-5 
decreased locomotor activity2 supporting datasetsAtg2bem1(IMPC)JhomozygoteEarly adult1.62x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Atg2bem1(IMPC)JExon Deletionmouse

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