Hibch | 3-hydroxyisobutyryl-Coenzyme A hydrolase
Physiological systems
20 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Embryo Growth/size/body region Nervous system Mortality/aging Renal/urinary system
15 No significant impact
4 Not tested
Data collections
Gene metrics:10Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal neural tube morphology | 1 supporting dataset | Hibchem1(IMPC)Tcp | homozygote | E9.5 | N/A * | ||
| abnormal neural tube closure | 1 supporting dataset | Hibchem1(IMPC)Tcp | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Hibchem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| abnormal neural tube closure | 1 supporting dataset | Hibchem1(IMPC)Tcp | heterozygote | E9.5 | N/A * | ||
| abnormal forebrain development | 1 supporting dataset | Hibchem1(IMPC)Tcp | heterozygote | E9.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Hibchem1(IMPC)Tcp | heterozygote | E9.5 | N/A * | ||
| abnormal kidney morphology | 1 supporting dataset | Hibchem1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| abnormal hindbrain development | 1 supporting dataset | Hibchem1(IMPC)Tcp | homozygote | E9.5 | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Hibchem1(IMPC)Tcp | homozygote | E12.5 | N/A * | ||
| abnormal midbrain development | 1 supporting dataset | Hibchem1(IMPC)Tcp | heterozygote | E9.5 | N/A * |
| | | | | | | | | | |
External links
No external links available for Hibch.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Hibchem1(IMPC)Tcp | Exon Deletion | | mouse |
| Hibchtm49654(L1L2_Pgk_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |