Commd9 | COMM domain containing 9

GeneMGI:1923751Synonyms: 1810029F08Rik

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Vision/eye Hematopoietic system Behavior/neurological Mortality/aging

13 No significant impact

5 Not tested

Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

decreased hemoglobin content1 supporting datasetCommd9tm1b(KOMP)WtsiheterozygoteEarly adult1.41x10-6 
increased neutrophil cell number2 supporting datasetsCommd9tm1b(KOMP)WtsiheterozygoteEarly adult1.94x10-8 
abnormal iris morphology1 supporting datasetCommd9tm1b(KOMP)WtsiheterozygoteEarly adult8.1x10-5 
impaired glucose tolerance1 supporting datasetCommd9tm1b(KOMP)WtsiheterozygoteEarly adult3.12x10-5 
decreased lymphocyte cell number1 supporting datasetCommd9tm1b(KOMP)WtsiheterozygoteEarly adult1.15x10-7 
decreased locomotor activity5 supporting datasetsCommd9tm1b(KOMP)WtsiheterozygoteEarly adult4.3x10-6 
decreased circulating fructosamine level1 supporting datasetCommd9tm1b(KOMP)WtsiheterozygoteEarly adult4.88x10-6 
increased red blood cell distribution width1 supporting datasetCommd9tm1b(KOMP)WtsiheterozygoteEarly adult8.69x10-5 
decreased erythrocyte cell number1 supporting datasetCommd9tm1b(KOMP)WtsiheterozygoteEarly adult1.02x10-5 
preweaning lethality, complete penetrance1 supporting datasetCommd9tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Commd9tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Commd9tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Commd9tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Commd9tm1e(KOMP)MbpTargeted, non-conditional allelees cell
Commd9tm1e(KOMP)WtsiTargeted, non-conditional allelees cell

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