Wdr62 | WD repeat domain 62
Physiological systems
19 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Nervous system Vision/eye Renal/urinary system
12 No significant impact
5 Not tested
Data collections
Gene metrics:13Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| male infertility | 1 supporting dataset | Wdr62em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| small kidney | 1 supporting dataset | Wdr62em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| small seminal vesicle | 1 supporting dataset | Wdr62em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| increased circulating sodium level | 1 supporting dataset | Wdr62em1(IMPC)Tcp | homozygote | Early adult | 1.04x10-5 | ||
| enlarged lymph nodes | 1 supporting dataset | Wdr62em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| microphthalmia | 1 supporting dataset | Wdr62em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| decreased prepulse inhibition | 1 supporting dataset | Wdr62em1(IMPC)Tcp | homozygote | Early adult | 4.73x10-5 | ||
| small testis | 1 supporting dataset | Wdr62em1(IMPC)Tcp | homozygote | Early adult | N/A * |
| | | | | | | | | | |
Human diseases caused by Wdr62 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Wdr62.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Wdr62em1(IMPC)Tcp | Exon Deletion | | mouse |
| Wdr62tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Wdr62tm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Wdr62tm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Wdr62tm3a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Wdr62tm3e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |