Wdr62 | WD repeat domain 62

GeneMGI:1923696Synonyms: 2310038K02Rik

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Nervous system Vision/eye Renal/urinary system

12 No significant impact

5 Not tested

Gene metrics:13Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

male infertility1 supporting datasetWdr62em1(IMPC)TcphomozygoteEarly adultN/A * 
small kidney1 supporting datasetWdr62em1(IMPC)TcphomozygoteEarly adultN/A * 
small seminal vesicle1 supporting datasetWdr62em1(IMPC)TcphomozygoteEarly adultN/A * 
increased circulating sodium level1 supporting datasetWdr62em1(IMPC)TcphomozygoteEarly adult1.04x10-5 
enlarged lymph nodes1 supporting datasetWdr62em1(IMPC)TcphomozygoteEarly adultN/A * 
microphthalmia1 supporting datasetWdr62em1(IMPC)TcphomozygoteEarly adultN/A * 
decreased prepulse inhibition1 supporting datasetWdr62em1(IMPC)TcphomozygoteEarly adult4.73x10-5 
small testis1 supporting datasetWdr62em1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Wdr62em1(IMPC)TcpExon Deletionmouse
Wdr62tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Wdr62tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Wdr62tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Wdr62tm3a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Wdr62tm3e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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