Churc1 | churchill domain containing 1

GeneMGI:1923684Synonyms: chch, My015, +1 more

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Immune system Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Cardiovascular system

15 No significant impact

3 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:78Adult tissues
27Embryo tissues

Phenotypes

enlarged thymus1 supporting datasetChurc1tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
abnormal thymus morphology1 supporting datasetChurc1tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
enlarged heart1 supporting datasetChurc1tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetChurc1tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
abnormal heart morphology1 supporting datasetChurc1tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
increased effector memory T-helper cell number1 supporting datasetChurc1tm1b(EUCOMM)WtsihomozygoteEarly adult1.07x10-7 
abnormal eye morphology1 supporting datasetChurc1tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Churc1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Churc1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Churc1tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Churc1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Churc1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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