Sun5 | Sad1 and UNC84 domain containing 5
Physiological systems
20 / 24 physiological systems tested
9 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Cardiovascular system
11 No significant impact
4 Not tested
Data collections
Gene metrics:12Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased circulating calcium level | 1 supporting dataset | Sun5em1(IMPC)Mbp | homozygote | Early adult | 1.27x10-5 | ||
| enlarged spleen | 1 supporting dataset | Sun5em1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
| male infertility | 1 supporting dataset | Sun5em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| enlarged lymph nodes | 2 supporting datasets | Sun5em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal liver morphology | 1 supporting dataset | Sun5em1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
| abnormal spleen morphology | 1 supporting dataset | Sun5em1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
| abnormal lymph node morphology | 2 supporting datasets | Sun5em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| thrombocytopenia | 1 supporting dataset | Sun5em1(IMPC)Mbp | homozygote | Late adult | 1.8x10-5 | ||
| abnormal testis morphology | 1 supporting dataset | Sun5em1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
| prolonged QT interval | 1 supporting dataset | Sun5em1(IMPC)Mbp | homozygote | Late adult | 1.81x10-6 |
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Human diseases caused by Sun5 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Sun5.
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