Trmt5 | TRM5 tRNA methyltransferase 5
Physiological systems
14 / 24 physiological systems tested
1 Significantly impacted by the knock-out
Mortality/aging
13 No significant impact
10 Not tested
Data collections
Gene metrics:1Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Trmt5em1(IMPC)Bay | homozygote | Early adult | N/A * |
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Human diseases caused by Trmt5 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Trmt5.
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| Trmt5em1(IMPC)Bay | Exon Deletion | | mouse |
| Trmt5tm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Trmt5tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Trmt5tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |