Zdhhc5 | zinc finger, DHHC domain containing 5

GeneMGI:1923573Synonyms: Zisp, 1110032A17Rik

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region Hearing/vestibular/ear Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



polycystic kidney	1 supporting dataset	Zdhhc5^{tm1e.1(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
decreased total retina thickness	2 supporting datasets	Zdhhc5^{tm1e.1(EUCOMM)Hmgu}	homozygote	Early adult	5.53x10^-12
decreased startle reflex	1 supporting dataset	Zdhhc5^{tm1e.1(EUCOMM)Hmgu}	homozygote	Early adult	6.92x10^-6
decreased total body fat amount	1 supporting dataset	Zdhhc5^{tm1e.1(EUCOMM)Hmgu}	homozygote	Early adult	9.76x10^-5
shortened PR interval	1 supporting dataset	Zdhhc5^{tm1e.1(EUCOMM)Hmgu}	homozygote	Early adult	2.3x10^-5
abnormal auditory brainstem response	1 supporting dataset	Zdhhc5^{tm1e.1(EUCOMM)Hmgu}	homozygote	Early adult	5.74x10^-5
increased mean platelet volume	1 supporting dataset	Zdhhc5^{tm1e.1(EUCOMM)Hmgu}	homozygote	Early adult	1.55x10^-15
abnormal retina vasculature morphology	1 supporting dataset	Zdhhc5^{tm1e.1(EUCOMM)Hmgu}	homozygote	Early adult	7.14x10^-7
abnormal retina morphology	1 supporting dataset	Zdhhc5^{tm1e.1(EUCOMM)Hmgu}	homozygote	Early adult	3.93x10^-12

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Zdhhc5.

Associated images

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Histopathology

There is no histopathology data found for Zdhhc5.

IMPC related publications

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External links

No external links available for Zdhhc5.

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*Zdhhc5^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Zdhhc5^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell mouse
*Zdhhc5^{tm1e.1(EUCOMM)Hmgu}*	Promoter excision from Targeted, non-conditional allele	‌	mouse
*Zdhhc5^{tm39351(L1L2_st2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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