Tsen54 | tRNA splicing endonuclease subunit 54

GeneMGI:1923515Synonyms: 0610034P02Rik

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
5Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased grip strength3 supporting datasetsTsen54em1(IMPC)JheterozygoteEarly adult2.18x10-7 
embryonic lethality prior to organogenesis1 supporting datasetTsen54em1(IMPC)JhomozygoteE9.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetTsen54em1(IMPC)JhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Tsen54em1(IMPC)JExon Deletionmouse
Tsen54tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Tsen54tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Tsen54tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Tsen54tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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