Coa5 | cytochrome C oxidase assembly factor 5
Physiological systems
20 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Reproductive system Integument Endocrine/exocrine gland Embryo Growth/size/body region Behavior/neurological Mortality/aging
13 No significant impact
4 Not tested
Data collections
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
29Embryo tissues
| abnormal embryo size | 1 supporting dataset | Coa5tm1b(KOMP)Wtsi | heterozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Coa5tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| decreased locomotor activity | 1 supporting dataset | Coa5tm1b(KOMP)Wtsi | heterozygote | Early adult | 4.92x10-6 | ||
| small adrenal glands | 1 supporting dataset | Coa5tm1b(KOMP)Wtsi | heterozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Coa5tm1b(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Coa5tm1b(KOMP)Wtsi | homozygote | E12.5 | N/A * | ||
| pallor | 1 supporting dataset | Coa5tm1b(KOMP)Wtsi | heterozygote | E9.5 | N/A * | ||
| abnormal uterus morphology | 1 supporting dataset | Coa5tm1b(KOMP)Wtsi | heterozygote | Early adult | N/A * |
| | | | | | | | | | |
External links
No external links available for Coa5.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Coa5tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Coa5tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Coa5tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Coa5tm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |