Stx16 | syntaxin 16

GeneMGI:1923396Synonyms: 5430410K23Rik, SYN16, +1 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Behavior/neurological Skeleton

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

2Associated diseases

Expression examined in:49Adult tissues

25Embryo tissues

Phenotypes

Phy. System:



increased circulating alkaline phosphatase level	1 supporting dataset	Stx16^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.2x10^-5
increased circulating alanine transaminase level	1 supporting dataset	Stx16^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.17x10^-7
hyperactivity	8 supporting datasets	Stx16^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.19x10^-11
increased circulating potassium level	1 supporting dataset	Stx16^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.02x10^-5
increased bone mineral content	1 supporting dataset	Stx16^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.39x10^-5
increased exploration in new environment	1 supporting dataset	Stx16^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.48x10^-8
increased lean body mass	2 supporting datasets	Stx16^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.66x10^-7
decreased thigmotaxis	2 supporting datasets	Stx16^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.14x10^-8
increased fasting circulating glucose level	1 supporting dataset	Stx16^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.1x10^-6
decreased circulating serum albumin level	1 supporting dataset	Stx16^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.51x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Stx16.

Associated images

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Histopathology

There is no histopathology data found for Stx16.

IMPC related publications

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External links

No external links available for Stx16.

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*Stx16^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Stx16^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Stx16^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Stx16^{tm301848(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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