Zmym2 | zinc finger, MYM-type 2

GeneMGI:1923257Synonyms: Zfp198, MYM, +3 more

Physiological systems

19 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Adipose tissue Embryo Growth/size/body region Nervous system Vision/eye Hematopoietic system Behavior/neurological Mortality/aging Cardiovascular system

8 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:19Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:

Life Stage:



increased leukocyte cell number	1 supporting dataset	Zmym2^em1(IMPC)J	heterozygote	Early adult	1.25x10^-5
preweaning lethality, complete penetrance	3 supporting datasets	Zmym2^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
abnormal retina outer nuclear layer morphology	2 supporting datasets	Zmym2^em1(IMPC)Bay	heterozygote	Early adult	2.67x10^-5
abnormal hindbrain development	1 supporting dataset	Zmym2^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal neural tube morphology	1 supporting dataset	Zmym2^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal somite shape	1 supporting dataset	Zmym2^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
increased total body fat amount	2 supporting datasets	Zmym2^em1(IMPC)J	heterozygote	Early adult	1.17x10^-5
increased startle reflex	1 supporting dataset	Zmym2^em1(IMPC)J	heterozygote	Early adult	1.77x10^-6
increased exploration in new environment	1 supporting dataset	Zmym2^em1(IMPC)J	heterozygote	Early adult	9.26x10^-5
abnormal heart morphology	1 supporting dataset	Zmym2^em1(IMPC)Bay	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Zmym2.

Associated images

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Histopathology

There is no histopathology data found for Zmym2.

IMPC related publications

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External links

No external links available for Zmym2.

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*Zmym2^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Zmym2^em1(IMPC)J*	Exon Deletion	‌	mouse
*Zmym2^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Zmym2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Zmym2^{tm449824(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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