Slain2 | SLAIN motif family, member 2

GeneMGI:1923241Synonyms: 5033405K12Rik, 8030444K12Rik

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Behavior/neurological Mortality/aging

15 No significant impact

5 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetSlain2em1(IMPC)JhomozygoteEarly adultN/A * 
decreased circulating triglyceride level1 supporting datasetSlain2em1(IMPC)JheterozygoteEarly adult4.57x10-7 
hyperactivity2 supporting datasetsSlain2em1(IMPC)JheterozygoteEarly adult6.18x10-5 
decreased circulating cholesterol level1 supporting datasetSlain2em1(IMPC)JheterozygoteEarly adult2.83x10-5 
decreased circulating bilirubin level1 supporting datasetSlain2em1(IMPC)JheterozygoteEarly adult2.77x10-6 
abnormal coat/ hair morphology1 supporting datasetSlain2em1(IMPC)JheterozygoteEarly adult2.24x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Slain2em1(IMPC)JExon Deletionmouse
Slain2tm1(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell

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