Slain2 | SLAIN motif family, member 2
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Integument Behavior/neurological Mortality/aging
15 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 1 supporting dataset | Slain2em1(IMPC)J | homozygote | Early adult | N/A * | ||
| decreased circulating triglyceride level | 1 supporting dataset | Slain2em1(IMPC)J | heterozygote | Early adult | 4.57x10-7 | ||
| hyperactivity | 2 supporting datasets | Slain2em1(IMPC)J | heterozygote | Early adult | 6.18x10-5 | ||
| decreased circulating cholesterol level | 1 supporting dataset | Slain2em1(IMPC)J | heterozygote | Early adult | 2.83x10-5 | ||
| decreased circulating bilirubin level | 1 supporting dataset | Slain2em1(IMPC)J | heterozygote | Early adult | 2.77x10-6 | ||
| abnormal coat/ hair morphology | 1 supporting dataset | Slain2em1(IMPC)J | heterozygote | Early adult | 2.24x10-8 |
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Human diseases caused by Slain2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Slain2.
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| Slain2em1(IMPC)J | Exon Deletion | | mouse |
| Slain2tm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |