Saxo1 | stabilizer of axonemal microtubules 1

GeneMGI:1923061Synonyms: 4930500O09Rik, Fam154a

Physiological systems

16 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological

11 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased eosinophil cell number	1 supporting dataset	Saxo1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.5x10^-5
abnormal vitreous body morphology	1 supporting dataset	Saxo1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.52x10^-5
hyperactivity	2 supporting datasets	Saxo1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.82x10^-6
decreased body length	1 supporting dataset	Saxo1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.09x10^-5
decreased lymphocyte cell number	1 supporting dataset	Saxo1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.13x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Saxo1.

Associated images

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Histopathology

There is no histopathology data found for Saxo1.

IMPC related publications

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External links

No external links available for Saxo1.

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*Saxo1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Saxo1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Saxo1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Saxo1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Saxo1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Saxo1^{tm39111(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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