Saxo1 | stabilizer of axonemal microtubules 1
Physiological systems
16 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Immune system Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological
11 No significant impact
8 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased eosinophil cell number | 1 supporting dataset | Saxo1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 5.5x10-5 | ||
| abnormal vitreous body morphology | 1 supporting dataset | Saxo1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 7.52x10-5 | ||
| hyperactivity | 2 supporting datasets | Saxo1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.82x10-6 | ||
| decreased body length | 1 supporting dataset | Saxo1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.09x10-5 | ||
| decreased lymphocyte cell number | 1 supporting dataset | Saxo1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 4.13x10-6 |
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Human diseases caused by Saxo1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Saxo1.
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| Saxo1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Saxo1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Saxo1tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Saxo1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Saxo1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Saxo1tm39111(L1L2_gt2) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |