Smurf1 | SMAD specific E3 ubiquitin protein ligase 1

GeneMGI:1923038Synonyms: 4930431E10Rik

Physiological systems

19 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Behavior/neurological

18 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Zygosity:



hyperactivity	1 supporting dataset	Smurf1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.41x10^-5
trunk curl	1 supporting dataset	Smurf1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	5.57x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Smurf1.

Associated images

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Histopathology

There is no histopathology data found for Smurf1.

IMPC related publications

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External links

No external links available for Smurf1.

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*Smurf1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Smurf1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Smurf1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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