Egfem1 | EGF-like and EMI domain containing 1

GeneMGI:1922990Synonyms: 6130401L20Rik

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased mean corpuscular volume1 supporting datasetEgfem1em1(IMPC)JhomozygoteEarly adult1.4x10-6 
impaired glucose tolerance1 supporting datasetEgfem1em1(IMPC)JhomozygoteEarly adult7.69x10-5 
decreased fasting circulating glucose level1 supporting datasetEgfem1em1(IMPC)JhomozygoteEarly adult5.01x10-13 
increased circulating alkaline phosphatase level1 supporting datasetEgfem1em1(IMPC)JhomozygoteLate adult4.69x10-5 
abnormal startle reflex1 supporting datasetEgfem1em1(IMPC)JhomozygoteLate adult2.47x10-5 
hyperactivity1 supporting datasetEgfem1em1(IMPC)JhomozygoteLate adult3.44x10-10 
increased mean corpuscular hemoglobin concentration1 supporting datasetEgfem1em1(IMPC)JhomozygoteEarly adult9.06x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Egfem1em1(IMPC)JExon Deletionmouse
Egfem1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Egfem1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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