Kdm5b | lysine demethylase 5B

GeneMGI:1922855Synonyms: Jarid1b, Plu1, +5 more

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Growth/size/body region Behavior/neurological Mortality/aging

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

absent pinna reflex1 supporting datasetKdm5bem1(IMPC)WtsihomozygoteEarly adult3.89x10-10 
preweaning lethality, incomplete penetrance1 supporting datasetKdm5bem1(IMPC)WtsihomozygoteEarly adultN/A * 
decreased body length1 supporting datasetKdm5bem1(IMPC)WtsihomozygoteEarly adult1.04x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Kdm5bem1(IMPC)WtsiDeletionmouse
Kdm5btm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Kdm5btm39833(pL1L2_GT0_bsd_frt15_neo_barcode)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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