Relch | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing

GeneMGI:1922832Synonyms: 2310035C23Rik

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Hearing/vestibular/ear Hematopoietic system Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased mean corpuscular volume1 supporting datasetRelchem1(IMPC)JhomozygoteEarly adult7.43x10-5 
abnormal auditory brainstem response5 supporting datasetsRelchem1(IMPC)JhomozygoteEarly adult6.54x10-13 
decreased mean corpuscular hemoglobin concentration1 supporting datasetRelchem1(IMPC)JhomozygoteEarly adult7.49x10-6 
hyperactivity6 supporting datasetsRelchem1(IMPC)JhomozygoteEarly adult1.62x10-7 
abnormal vocalization1 supporting datasetRelchem1(IMPC)JhomozygoteEarly adult1.69x10-6 
decreased startle reflex1 supporting datasetRelchem1(IMPC)JhomozygoteEarly adult6.68x10-7 
decreased exploration in new environment1 supporting datasetRelchem1(IMPC)JhomozygoteEarly adult5.27x10-5 
increased vertical activity1 supporting datasetRelchem1(IMPC)JhomozygoteEarly adult5.53x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Relchem1(IMPC)JExon Deletionmouse
Relchtm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Relchtm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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