Rsph9 | radial spoke head 9 homolog (Chlamydomonas)
Physiological systems
17 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Behavior/neurological Mortality/aging
15 No significant impact
7 Not tested
Data collections
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:41Adult tissues
0Embryo tissues
| hyperactivity | 1 supporting dataset | Rsph9tm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.09x10-8 | ||
| increased thigmotaxis | 2 supporting datasets | Rsph9tm1.1(KOMP)Vlcg | heterozygote | Early adult | 4.84x10-6 | ||
| preweaning lethality, incomplete penetrance | 3 supporting datasets | Rsph9tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| abnormal behavior | 1 supporting dataset | Rsph9tm1.1(KOMP)Vlcg | heterozygote | Early adult | 4.85x10-6 |
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| adrenal gland | heterozygote | Section images | 50% (1/2) | 0.7% (4/570) |
| aorta | heterozygote | n/a | 0% (0/2) | 0.19% (1/533) |
| brain | heterozygote | Section images | 100% (2/2) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | 0% (0/2) | 0.41% (2/490) |
| cartilage tissue | heterozygote | n/a | 0% (0/2) | 0.22% (1/454) |
| cerebellum | heterozygote | n/a | 0% (0/2) | 0.56% (3/532) |
| cerebral cortex | heterozygote | n/a | 0% (0/2) | 0.41% (2/491) |
| esophagus | heterozygote | n/a | 0% (0/2) | 1.67% (7/419) |
| eye | heterozygote | n/a | 0% (0/2) | 0% (0/335) |
| heart | heterozygote | n/a | 0% (0/2) | 0.36% (2/550) |
Human diseases caused by Rsph9 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Rsph9.
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| Rsph9tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Rsph9tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Rsph9tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Rsph9tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Rsph9tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |