Oplah | 5-oxoprolinase (ATP-hydrolysing)
GeneMGI:1922725
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system
12 No significant impact
7 Not tested
Data collections
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:140Adult tissues
0Embryo tissues
| decreased circulating unsaturated transferrin level | 1 supporting dataset | Oplahtm1b(KOMP)Wtsi | homozygote | Early adult | 7.15x10-5 | ||
| abnormal lens morphology | 1 supporting dataset | Oplahtm1b(KOMP)Wtsi | homozygote | Early adult | 8.53x10-10 | ||
| decreased heart rate | 1 supporting dataset | Oplahtm1b(KOMP)Wtsi | homozygote | Early adult | 5.07x10-8 | ||
| increased startle reflex | 1 supporting dataset | Oplahtm1b(KOMP)Wtsi | homozygote | Early adult | 3.24x10-6 | ||
| cataract | 1 supporting dataset | Oplahtm1b(KOMP)Wtsi | homozygote | Early adult | 4.09x10-10 | ||
| decreased red blood cell distribution width | 1 supporting dataset | Oplahtm1b(KOMP)Wtsi | homozygote | Early adult | 3.57x10-6 |
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External links
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| Oplahtm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Oplahtm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Oplahtm1e(KOMP)Wtsi | Targeted, non-conditional allele | | es cell |