Ascc2 | activating signal cointegrator 1 complex subunit 2
Physiological systems
21 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Behavior/neurological Mortality/aging Cardiovascular system
14 No significant impact
3 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
62Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Ascc2tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| decreased heart left ventricle size | 1 supporting dataset | Ascc2tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 1.05x10-6 | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Ascc2tm1a(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| trunk curl | 1 supporting dataset | Ascc2tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 7.17x10-7 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Ascc2tm1b(EUCOMM)Wtsi | homozygote | E9.5 | N/A * | ||
| increased circulating chloride level | 1 supporting dataset | Ascc2tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 7.31x10-10 | ||
| enlarged spleen | 1 supporting dataset | Ascc2tm1a(EUCOMM)Wtsi | heterozygote | Early adult | N/A * |
| | | | | | | | | | |
External links
No external links available for Ascc2.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Ascc2tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Ascc2tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Ascc2tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Ascc2tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |