Secisbp2 | SECIS binding protein 2

GeneMGI:1922670Synonyms: 2210413N07Rik, SBP2, +1 more

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Vision/eye Hematopoietic system Mortality/aging

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:



decreased circulating sodium level	1 supporting dataset	Secisbp2^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	8.5x10^-6
increased leukocyte cell number	1 supporting dataset	Secisbp2^{tm1c(EUCOMM)Wtsi}	homozygote	Early adult	2.19x10^-6
abnormal retina morphology	1 supporting dataset	Secisbp2^{tm1c(EUCOMM)Wtsi}	homozygote	Early adult	1.06x10^-6
decreased leukocyte cell number	1 supporting dataset	Secisbp2^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	7.14x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Secisbp2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased NK cell number	1 supporting dataset	Secisbp2^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	9.29x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Secisbp2.

Associated images

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Histopathology

There is no histopathology data found for Secisbp2.

IMPC related publications

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External links

No external links available for Secisbp2.

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*Secisbp2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Secisbp2^{tm1c(EUCOMM)Wtsi}*	Wild type floxed exon (post-Flp)	‌	mouse

My Genes