Ndufs7 | NADH:ubiquinone oxidoreductase core subunit S7

GeneMGI:1922656Synonyms: 1010001M04Rik

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Integument Embryo Growth/size/body region Limbs/digits/tail Vision/eye Hematopoietic system Mortality/aging

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

2Associated diseases

Expression examined in:50Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased total retina thickness	1 supporting dataset	Ndufs7^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	6.23x10^-6
preweaning lethality, complete penetrance	3 supporting datasets	Ndufs7^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
embryonic growth retardation	1 supporting dataset	Ndufs7^{tm1b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Ndufs7^{tm1b(EUCOMM)Hmgu}	heterozygote	E9.5	N/A ^*
decreased hemoglobin content	1 supporting dataset	Ndufs7^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.78x10^-5
abnormal digit morphology	1 supporting dataset	Ndufs7^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.18x10^-5
abnormal coat/ hair morphology	1 supporting dataset	Ndufs7^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	8.41x10^-6
abnormal embryo size	1 supporting dataset	Ndufs7^{tm1b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*
abnormal embryo turning	1 supporting dataset	Ndufs7^{tm1b(EUCOMM)Hmgu}	heterozygote	E9.5	N/A ^*
abnormal skin coloration	1 supporting dataset	Ndufs7^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.28x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ndufs7.

Associated images

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Histopathology

There is no histopathology data found for Ndufs7.

IMPC related publications

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External links

No external links available for Ndufs7.

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*Ndufs7^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Ndufs7^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ndufs7^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ndufs7^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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