Nxnl2 | nucleoredoxin-like 2

GeneMGI:1922374Synonyms: 4930519N16Rik

Physiological systems

22 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Immune system Integument Endocrine/exocrine gland Growth/size/body region Muscle Hematopoietic system

16 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



enlarged thymus	1 supporting dataset	Nxnl2^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Nxnl2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal skeletal muscle morphology	1 supporting dataset	Nxnl2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal coat/ hair morphology	1 supporting dataset	Nxnl2^{em1(IMPC)Ccpcz}	heterozygote	Early adult	3.78x10^-5
enlarged spleen	1 supporting dataset	Nxnl2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Nxnl2^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
decreased lean body mass	2 supporting datasets	Nxnl2^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.62x10^-5
abnormal thymus morphology	1 supporting dataset	Nxnl2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Nxnl2^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Nxnl2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nxnl2.

Associated images

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Histopathology

There is no histopathology data found for Nxnl2.

IMPC related publications

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External links

No external links available for Nxnl2.

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*Nxnl2^{em1(IMPC)Ccpcz}*	Intra-exon deletion	‌	mouse
*Nxnl2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Nxnl2^{tm415883(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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