Usp50 | ubiquitin specific peptidase 50

GeneMGI:1922333Synonyms: 1700086G18Rik, 4930511O11Rik

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Nervous system Vision/eye Mortality/aging

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Usp50^{tm1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
decreased prepulse inhibition	1 supporting dataset	Usp50^{tm1(KOMP)Vlcg}	heterozygote	Early adult	6.51x10^-5
irregularly shaped pupil	1 supporting dataset	Usp50^{tm1(KOMP)Vlcg}	heterozygote	Early adult	1.7x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Usp50.

Associated images

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Histopathology

There is no histopathology data found for Usp50.

IMPC related publications

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External links

No external links available for Usp50.

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*Usp50^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Usp50^{tm114861(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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