Miga2 | mitoguardin 2

GeneMGI:1922035Synonyms: Fam73b, R74766, +1 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Growth/size/body region Hematopoietic system Skeleton Craniofacial

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased body weight	5 supporting datasets	Miga2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	7.33x10^-19
decreased hematocrit	1 supporting dataset	Miga2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	3.61x10^-5
abnormal snout morphology	1 supporting dataset	Miga2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.25x10^-5
abnormal cranium morphology	1 supporting dataset	Miga2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	5.71x10^-9
decreased hemoglobin content	1 supporting dataset	Miga2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	5.36x10^-6
abnormal tooth morphology	1 supporting dataset	Miga2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	8.73x10^-9
abnormal maxilla morphology	1 supporting dataset	Miga2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	6x10^-5
decreased erythrocyte cell number	1 supporting dataset	Miga2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	5.42x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Miga2.

Associated images

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Histopathology

There is no histopathology data found for Miga2.

IMPC related publications

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External links

No external links available for Miga2.

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*Miga2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Miga2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Miga2^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Miga2^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Miga2^{tm357788(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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