Trmo | tRNA methyltransferase O

GeneMGI:1922003Synonyms: 5830415F09Rik

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased lactate dehydrogenase level	1 supporting dataset	Trmo^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.26x10^-8
increased circulating alanine transaminase level	1 supporting dataset	Trmo^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.09x10^-7
abnormal behavior	3 supporting datasets	Trmo^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.86x10^-7
increased circulating aspartate transaminase level	1 supporting dataset	Trmo^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.19x10^-7
increased circulating glycerol level	1 supporting dataset	Trmo^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.54x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Trmo.

Associated images

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Histopathology

There is no histopathology data found for Trmo.

IMPC related publications

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External links

No external links available for Trmo.

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*Trmo^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Trmo^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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