C2cd5 | C2 calcium-dependent domain containing 5

GeneMGI:1921991Synonyms: CDP138, 5730419I09Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Nervous system Vision/eye Hematopoietic system Mortality/aging Cardiovascular system

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased mean corpuscular hemoglobin	1 supporting dataset	C2cd5^em1(IMPC)Tcp	homozygote	Early adult	2.13x10^-10
decreased prepulse inhibition	1 supporting dataset	C2cd5^em1(IMPC)Tcp	homozygote	Early adult	3.57x10^-5
decreased mean corpuscular volume	1 supporting dataset	C2cd5^em1(IMPC)Tcp	homozygote	Early adult	1.3x10^-6
abnormal retina vasculature morphology	1 supporting dataset	C2cd5^em1(IMPC)Tcp	homozygote	Early adult	2.5x10^-9
abnormal retina morphology	1 supporting dataset	C2cd5^em1(IMPC)Tcp	homozygote	Early adult	5.95x10^-11
preweaning lethality, incomplete penetrance	1 supporting dataset	C2cd5^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal retina blood vessel morphology	1 supporting dataset	C2cd5^em1(IMPC)Tcp	homozygote	Early adult	6.55x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for C2cd5.

Associated images

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Histopathology

There is no histopathology data found for C2cd5.

IMPC related publications

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External links

No external links available for C2cd5.

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*C2cd5^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*C2cd5^{tm179771(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*C2cd5^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*C2cd5^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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